BDBM686253 US20240245694, Example 19B

SMILES Cc1cc(ccc1NC(=O)[C@@H]1CCc2c(N3CCN(CC3)C(=O)c3nccc(Cl)c3O)c(=O)n3nc(nc3n12)C1=CCOCC1)C(F)(F)F

InChI Key InChIKey=NQCVYPSJKLMIQC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 686253   

TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1238](Human)
Novartis

US Patent

LigandBDBM686253(US20240245694, Example 19B)Copy SMILESCopy InChI

Affinity DataIC50: 4.40E+4nMAssay Description:The core helicase motif of the WRN protein (aa N517-P1238) was produced for this assay (protein production as described above). A 45 oligonucleotide ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/7/2024
Entry Details
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