BDBM686059 US20240245673, Example 211

SMILES CN1CCN(CC1)c1ccc(C)c(c1)C(=O)NC1(CC1)c1cc(nc2ccccc12)-c1cnn(C)c1

InChI Key InChIKey=MMVYUHFDLZLNDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 686059   

TargetReplicase polyprotein 1a(2019-nCoV)
Pfizer

US Patent
LigandPNGBDBM686059(US20240245673, Example 211)
Affinity DataIC50: 3nMAssay Description:The potency of compounds against the SARS-CoV-2 Papain like protease (PLpro) was measured using a synthetic profluorogenic substrate Z-RLRGG-AMC. Com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM686059(US20240245673, Example 211)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed