BDBM685896 US12043625, Example 4.01

SMILES OC(=O)[C@@H]1C[C@@H](CN1c1nc(nc2c3ccccc3oc12)C(F)(F)F)Oc1ncc(cc1C12CC1COCC2)C#C

InChI Key InChIKey=AFXJXMOCAJITLM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685896   

TargetCyclic GMP-AMP synthase(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM685896(US12043625, Example 4.01)
Affinity DataIC50: 8nMAssay Description:PKC-theta and PKC-delta biochemical activities were measured using the PKC-theta HTRF KinEASEkit kit, according to manufacturer's instructions (C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
Go to US Patent