BDBM685836 US12043602, Compound 7

SMILES [#6]-[#8]-c1ccc(cc1)-[#6@@H](-[#6])-[#7](-[#6]\[#6]=[#6](/c1ccccc1)-c1ccccc1)-[#6]\[#6]=[#6](/c1ccccc1)-c1ccccc1

InChI Key InChIKey=GYDJAJZOLDJGNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 685836   

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685836(US12043602, Compound 7)
Affinity DataIC50: 500nMAssay Description:Table 9: IC50: 50% inhibitory concentration for KRASG12V mislocalization. Values were calculated from at least eight data points. In general, at leas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
Go to US Patent

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685836(US12043602, Compound 7)
Affinity DataIC50: 500nMAssay Description:Table 10: IC50: 50% inhibitory concentration for KRASG12V mislocalization. Values were calculated from at least eight data points. In general, at lea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
Go to US Patent