BDBM685801 N-(3,3-diphenylallyl)-1-phenyl-N-(2- (pyrrolidin-1-yl)ethyl)cyclopropanamine::US12043602, Compound NY0444

SMILES [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-1)-[#7](-[#6]\[#6]=[#6](\c1ccccc1)-c1ccccc1)C1([#6]-[#6]1)c1ccccc1

InChI Key InChIKey=XGTXJIOYBOLHDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685801   

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685801(US12043602, Compound NY0444 | N-(3,3-diphenylallyl...)
Affinity DataIC50: 730nMAssay Description:Table 3: Potency and efficacy K-RAS inhibition and toxicity of batch 3 compounds. MDCK cells co-expressing GFP-K-RASG12V and mCherry-CAAX were grown ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
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