BDBM685765 1-(3,3-diphenylallyl)-6-fluoro-1,2,3,4- tetrahydroquinoline::US12043602, Compound NY0293

SMILES Fc1ccc2-[#7](-[#6]\[#6]=[#6](\c3ccccc3)-c3ccccc3)-[#6]-[#6]-[#6]-c2c1

InChI Key InChIKey=WXAVIYAWLYMUSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685765   

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685765(US12043602, Compound NY0293 | 1-(3,3-diphenylallyl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Table 1: Potency and efficacy of K-RAS inhibition and toxicity of batch1 and 2 compounds. MDCK cells co-expressing GFP-K-RASG12V and mCherry-CAAX wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
Go to US Patent