BDBM685764 US12043602, Compound 12f::US12043602, Compound NY0244b
SMILES [#6]-[#8]-c1ccc(cc1)-[#6@@H](-[#6])-[#7](-[#6]-[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6])-[#6]-[#6]-1)-[#6]\[#6]=[#6](/c1ccccc1)-c1ccccc1
InChI Key InChIKey=NZNBIFCXBANXNS-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 685764
Affinity DataIC50: 1.76E+3nMAssay Description:Table 1: Potency and efficacy of K-RAS inhibition and toxicity of batch1 and 2 compounds. MDCK cells co-expressing GFP-K-RASG12V and mCherry-CAAX wer...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Table 9: IC50: 50% inhibitory concentration for KRASG12V mislocalization. Values were calculated from at least eight data points. In general, at leas...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Table 10: IC50: 50% inhibitory concentration for KRASG12V mislocalization. Values were calculated from at least eight data points. In general, at lea...More data for this Ligand-Target Pair