BDBM685752 (1R,2S)-N,N-bis(3,3-diphenylallyl)-2- phenylcyclopropanamine::US12043602, Compound NY022601

SMILES [#6](\[#6]=[#6](\c1ccccc1)-c1ccccc1)-[#7](-[#6]\[#6]=[#6](\c1ccccc1)-c1ccccc1)-[#6]-1-[#6]-[#6@H]-1-c1ccccc1

InChI Key InChIKey=OWRDMFRDJGZCNA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685752   

TargetGTPase KRas [G12V](Human)
University of Texas

US Patent
LigandPNGBDBM685752(US12043602, Compound NY022601 | (1R,2S)-N,N-bis(3,...)
Affinity DataIC50: 420nMAssay Description:Table 1: Potency and efficacy of K-RAS inhibition and toxicity of batch1 and 2 compounds. MDCK cells co-expressing GFP-K-RASG12V and mCherry-CAAX wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2024
Entry Details
Go to US Patent