BDBM685600 US20240239812, Compound 24::US20240239812, Compound 26

SMILES COC1[C@@H]2OCC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ccc(cc23)C(=O)N=[S@@](=O)(C[C@@H](C)C\C=C1/F)NC(=O)c1cn(C)nc1OC

InChI Key InChIKey=VFFBTCWSTVFCJE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 685600   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM685600(US20240239812, Compound 26 | US20240239812, Compou...)
Affinity DataKi:  0.0110nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM685600(US20240239812, Compound 26 | US20240239812, Compou...)
Affinity DataKi:  5.12nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent