BDBM685588 US20240239812, Compound 12

SMILES CO[C@@H]1[C@@H]2OCC[C@H]2CN2C[C@@]3(CCCc4cc(Cl)ccc34)COc3ncc(nc23)C(=O)NS(=O)(=O)[C@H](C)[C@@H](C)C\C=C1/F

InChI Key InChIKey=NXZDUGDBNWJJHK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685588   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM685588(US20240239812, Compound 12)
Affinity DataKi:  5.23nMAssay Description:The following assay and stock buffers were prepared for use in the assay: (a) Stock buffer: 10 mM Tris-HCl, pH=7.5+150 mM NaCl, filtered, sterilized,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent