BDBM685273 2-(benzotriazol-1-yl)-N-[(3,5-difluorophenyl)methyl]-N-(4-pyrrolidin-3-ylphenyl)acetamide::US20240239772, Compound 108

SMILES Fc1cc(F)cc(CN(C(=O)Cn2nnc3ccccc23)c2ccc(cc2)C2CCNC2)c1

InChI Key InChIKey=NXIKGSLCMDVNLG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685273   

TargetReplicase polyprotein 1ab(2019-nCoV)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM685273(US20240239772, Compound 108 | 2-(benzotriazol-1-yl...)
Affinity DataIC50: 210nMAssay Description:Protease activity and subsequent 10-point IC50 curves were spectroscopically determined using a scaled down, endpoint assay adapted from a previously...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent