BDBM685133 (S)-4-(3-(Dimethylamino)-3-(3-(trifluoromethyl)-phenethyl)piperidin-1-yl)-2-fluoro-N-(thiazol-2-yl)benzenesulfonamide, and (R)-4-(3-(dimethylamino)-3-(3-(trifluoromethyl)phenethyl)piperidin-1-yl)-2-fluoro-N-(thiazol-2-yl)benzenesulfonamide::US20240239766, Example 13

SMILES CN(C)[C@@]1(CCc2cccc(c2)C(F)(F)F)CCCN(C1)c1ccc(c(F)c1)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=OFDODRVFXOFXCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 685133   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM685133(US20240239766, Example 13 | (S)-4-(3-(Dimethylamin...)
Affinity DataIC50: 1.5nMAssay Description:The following voltage clamp electrophysiology studies are performed on representative compounds using cells heterologously expressing Nav1.7 or Nav1....More data for this Ligand-Target Pair
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Date in BDB:
10/30/2024
Entry Details
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