BDBM685120 US20240239763, Compound Formula I

SMILES OC(=O)c1ccc(cc1O)-c1sc(C#N)c2CCC(F)(F)Cc12

InChI Key InChIKey=UTTXOYFICPSQLS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 685120   

TargetXanthine dehydrogenase/oxidase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 21nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as decrease in uric acid level by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical Co.

US Patent
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds, standard inhibitors (at 100× final concentration), and mixed substrate working solutions were prepared; the microsomes (purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C9(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical Co.

US Patent
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 1.81E+4nMAssay Description:Test compounds, standard inhibitors (at 100× final concentration), and mixed substrate working solutions were prepared; the microsomes (purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical Co.

US Patent
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds, standard inhibitors (at 100× final concentration), and mixed substrate working solutions were prepared; the microsomes (purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical Co.

US Patent
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds, standard inhibitors (at 100× final concentration), and mixed substrate working solutions were prepared; the microsomes (purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Dongbao Purple Star (Hangzhou) Biopharmaceutical Co.

US Patent
LigandPNGBDBM685120(US20240239763, Compound Formula I)
Affinity DataIC50: 5.00E+4nMAssay Description:Test compounds, standard inhibitors (at 100× final concentration), and mixed substrate working solutions were prepared; the microsomes (purchased fro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
Go to US Patent