BDBM684720 N-Methyl-1′-((6-oxo-7-(trifluoromethyl)-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)-1′,2′,3′,6′-tetrahydro-[3,4′-bipyridine]-6-carboxamide::US20240228490, Example 84

SMILES CNC(=O)c1ccc(cn1)C1=CCN(Cc2cnc3cc(c(=O)[nH]c3c2)C(F)(F)F)CC1

InChI Key InChIKey=KMPYHGIMDJXSJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684720   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684720(US20240228490, Example 84 | N-Methyl-1′-((6-...)
Affinity DataIC50: 2.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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