BDBM684719 1′-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)-N-(2,2,2-trifluoroethyl)-1′,2′,3′,6′-tetrahydro-[3,4′-bipyridine]-6-carboxamide::US20240228490, Example 83

SMILES CCc1cc2ncc(CN3CCC(=CC3)c3ccc(nc3)C(=O)NCC(F)(F)F)cc2[nH]c1=O

InChI Key InChIKey=MTYITXSGKLGUFN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684719   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684719(US20240228490, Example 83 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 1.40nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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