BDBM684716 6-(4-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)piperazin-1-yl)-N-methylimidazo[1,5-a]pyridine-1-carboxamide::US20240228490, Example 80

SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc4c(ncn4c3)C(=O)NC)cc2[nH]c1=O

InChI Key InChIKey=KVYACXRSYYMCDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684716   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684716(US20240228490, Example 80 | 6-(4-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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