BDBM684707 7-((4-(1,5-Dimethyl-1H-imidazol-2-yl)-3,6-dihydropyridin-1(2H)-yl)methyl)-3-ethyl-1,5-naphthyridin-2(1H)-one::US20240228490, Example 53

SMILES CCc1cc2ncc(CN3CCC(=CC3)c3ncc(C)n3C)cc2[nH]c1=O

InChI Key InChIKey=DYSGNXQEADLDDC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684707   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684707(US20240228490, Example 53 | 7-((4-(1,5-Dimethyl-1H...)
Affinity DataIC50: 0.960nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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