BDBM684706 5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)-1,2,3,6-tetrahydropyridin-4-yl)-N-methylthiazole-2-carboxamide::US20240228490, Example 46::US20240228490, Example 82

SMILES CCc1cc2ncc(CN3CCC(=CC3)c3cnc(s3)C(=O)NC)cc2[nH]c1=O

InChI Key InChIKey=UBFZRAQLNNKKNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684706   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent