BDBM684700 4-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl)-1,2,3,6-tetrahydropyridin-4-yl)-2-fluoro-N-methylbenzamide::US20240228490, Example 33

SMILES CCc1cc2ncc(CN3CCC(=CC3)c3ccc(C(=O)NC)c(F)c3)cc2[nH]c1=O

InChI Key InChIKey=MBRLUFBQIRSVSY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684700   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684700(US20240228490, Example 33 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 0.910nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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