BDBM684695 3-Ethyl-7-((4-(2-methyl-1H-benzo[d]imidazol-6-yl)piperazin-1-yl)methyl)-1,5-naphthyridin-2(1H)-one::US20240228490, Example 24

SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc4nc(C)[nH]c4c3)cc2[nH]c1=O

InChI Key InChIKey=HFXWBQQHOWCFDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684695   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684695(US20240228490, Example 24 | 3-Ethyl-7-((4-(2-methy...)
Affinity DataIC50: 1.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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