BDBM684692 3-Ethyl-7-((4-(2-methyl-1-oxoisoindolin-5-yl)piperazin-1-yl)methyl)-1,5-naphthyridin-2(1H)-one::US20240228490, Example 6

SMILES CCc1cc2ncc(CN3CCN(CC3)c3ccc4C(=O)N(C)Cc4c3)cc2[nH]c1=O

InChI Key InChIKey=ORYJNYIPKWJMGX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684692   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684692(US20240228490, Example 6 | 3-Ethyl-7-((4-(2-methyl...)
Affinity DataIC50: 2.90nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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