BDBM684691 3-Ethyl-7-((4-(8-(methylamino)-1,7-naphthyridin-3-yl)piperazin-1-yl)methyl)-1,5-naphthyridin-2(1H)-one::US20240228490, Example 3

SMILES CCc1cc2ncc(CN3CCN(CC3)c3cnc4c(NC)nccc4c3)cc2[nH]c1=O

InChI Key InChIKey=RLNNRJHAIFVURX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684691   

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandPNGBDBM684691(US20240228490, Example 3 | 3-Ethyl-7-((4-(8-(methy...)
Affinity DataIC50: 0.400nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
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Date in BDB:
10/22/2024
Entry Details
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