BDBM684678 US20240228460, Compound (106)

SMILES O=C(NC(CNC(=O)c1cccc2cnsc12)c1ccccc1)C1COc2ccccc12

InChI Key InChIKey=DKZIBJRYMHQQNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684678   

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684678(US20240228460, Compound (106))
Affinity DataIC50: 8.90E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684678(US20240228460, Compound (106))
Affinity DataIC50: 1.02E+4nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent