BDBM684672 US20240228460, Compound (101)

SMILES Cc1cc[nH]c(=O)c1C(=O)NCC(NC(=O)c1cncc2ccccc12)c1ccc2ccccc2c1

InChI Key InChIKey=LPXXPLBNKLRBRN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684672   

TargetReplicase polyprotein 1a(2019-nCoV)
Variational AI

US Patent
LigandPNGBDBM684672(US20240228460, Compound (101))
Affinity DataIC50: 1.70E+3nMAssay Description:For select test compounds, the fluorogenic enzymatic assay measuring inhibition of SARS-CoV-2 Mpro was followed by a subsequent chromatographic purif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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TargetProcathepsin L(Human)
Variational AI

US Patent
LigandPNGBDBM684672(US20240228460, Compound (101))
Affinity DataIC50: 1.00E+5nMAssay Description:Assays to evaluate the inhibition of cathepsin L contained 25 pM cathepsin L (RD systems: 952-CY-010), 5 uM Z-LR-AMC fluorogenic peptide substrate, 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
Go to US Patent