BDBM684591 6'-(4-(tert-butyl)- piperazin-1-yl)-4- (3-chloro-4-(3- methyl-2-oxo-2,3- dihydro-1H-imid- azol-1-yl)phenyl)- 3-hydroxy-1',6- dimethyl-[2,4'- bipyridin]-2'(1'H)- one::US20240226096, Example I-9

SMILES Cc1cc(c(O)c(n1)-c1cc(N2CCN(CC2)C(C)(C)C)n(C)c(=O)c1)-c1ccc(c(Cl)c1)-n1ccn(C)c1=O

InChI Key InChIKey=RVYPUPJWBVQJFJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684591   

TargetBromodomain-containing protein 4 [368-440](Human)
Poseidon Innovation 1

US Patent
LigandPNGBDBM684591(US20240226096, Example I-9 | 6'-(4-(tert-butyl)- p...)
Affinity DataIC50: 87.2nMAssay Description:3x Complete Substrate plus Inhibitor Solution in Assay Medium (Opti-MEM I Reduced Serum Medium, no phenol red, and no serum) was prepared just before...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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