BDBM684584 1-(4-(5'-(4-(tert- butyl)piperazin-1- yl)-3-hydroxy-6'- methoxy-6-methyl- [2,3'-bipyridin]-4- yl)-2-chlorophen- yl)-3-methyl-1,3- dihydro-2H-imid- azol-2-one::US20240226096, Example I-3

SMILES COc1ncc(cc1N1CCN(CC1)C(C)(C)C)-c1nc(C)cc(c1O)-c1ccc(c(Cl)c1)-n1ccn(C)c1=O

InChI Key InChIKey=GGLQKJOSTVQFQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 684584   

TargetBromodomain-containing protein 4 [368-440](Human)
Poseidon Innovation 1

US Patent
LigandPNGBDBM684584(US20240226096, Example I-3 | 1-(4-(5'-(4-(tert- bu...)
Affinity DataIC50: 4.5nMAssay Description:3x Complete Substrate plus Inhibitor Solution in Assay Medium (Opti-MEM I Reduced Serum Medium, no phenol red, and no serum) was prepared just before...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
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