BDBM684561 US12030897, Example 1

SMILES Cc1cc(Nc2ncnn3ccc(CN4CCNCC4)c23)ccc1Oc1ccn2ncnc2c1

InChI Key InChIKey=AVXMDRDVYCBECO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 684561   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Medshine Discovery

US Patent
LigandPNGBDBM684561(US12030897, Example 1)
Affinity DataIC50: 24nMAssay Description:The object of this test is to detect the in vitro inhibitory activity of the compound against HER1 (ErbB1), HER2 (ErbB2) and HER4 (ErbB4). The enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetReceptor tyrosine-protein kinase erbB-4(Human)
Medshine Discovery

US Patent
LigandPNGBDBM684561(US12030897, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:The object of this test is to detect the in vitro inhibitory activity of the compound against HER1 (ErbB1), HER2 (ErbB2) and HER4 (ErbB4). The enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Medshine Discovery

US Patent
LigandPNGBDBM684561(US12030897, Example 1)
Affinity DataIC50: 1.00E+3nMAssay Description:The object of this test is to detect the in vitro inhibitory activity of the compound against HER1 (ErbB1), HER2 (ErbB2) and HER4 (ErbB4). The enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
US Patent