BDBM684511 3-ethynyl-8-(((1r,4r)-4-hydroxycyclohexyl)amino)-6-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)isoquinolin-1(2H)-one::US12030867, Compound 4k

SMILES Cc1nn(c2CC(C)(C)CC(=O)c12)-c1cc(N[C@H]2CC[C@H](O)CC2)c2c(c1)cc([nH]c2=O)C#C

InChI Key InChIKey=VSQQNEWLYAUDER-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 684511   

TargetHeat shock protein HSP 90-alpha(Human)
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM684511(US12030867, Compound 4k | 3-ethynyl-8-(((1r,4r)-4-...)
Affinity DataKd:  381nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent

TargetHeat shock protein HSP 90-beta(Human)
University of Notre Dame Du Lac

US Patent
LigandPNGBDBM684511(US12030867, Compound 4k | 3-ethynyl-8-(((1r,4r)-4-...)
Affinity DataKd:  337nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2024
Entry Details
Go to US Patent