BDBM683311 Preparation of (6-(4-aminopiperidin-1-yl)-2-(4-cyano-3-fluorophenyl)-3-(3-hydroxy-4-methoxyphenyl)pyridine-4-carbonitrile)::US20240216357, Example 273

SMILES COc1ccc(cc1O)-c1c(cc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1)C#N

InChI Key InChIKey=UFCQLHHSFDFXAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683311   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683311(US20240216357, Example 273 | Preparation of (6-(4-...)
Affinity DataIC50: 0.200nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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TargetCytochrome P450 3A4(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683311(US20240216357, Example 273 | Preparation of (6-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Using mixed human liver microsomes as a CYP 450 enzyme source, specific probe substrates of respective CYP isoenzymes (2 substrates for CYP 3A4) are ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent