BDBM683266 Preparation of 4-(2-(4-aminopiperidin-1-yl)-5-(3-hydroxy-4-methoxyphenyl)thiazol-4-yl)-2-fluorobenzonitrile::US20240216357, Example 223

SMILES COc1ccc(cc1O)-c1sc(nc1-c1ccc(C#N)c(F)c1)N1CCC(N)CC1

InChI Key InChIKey=SHFVJFNEKUYBAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683266   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683266(US20240216357, Example 223 | Preparation of 4-(2-(...)
Affinity DataIC50: 0.100nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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