BDBM683263 Preparation of 4-(2-(3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-5-(5-fluoro-3-methylbenzo[d]isoxazol-6-yl) thiazol-4-yl)-2-fluorobenzonitrile hydrochloride::US20240216357, Example 220

SMILES Cc1noc2cc(-c3sc(nc3-c3ccc(C#N)c(F)c3)C(=O)N3C4CCC3CC(N)C4)c(F)cc12

InChI Key InChIKey=LFPPYWLURQYYOB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683263   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683263(US20240216357, Example 220 | Preparation of 4-(2-(...)
Affinity DataIC50: 0.420nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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