BDBM683233 (R)-4-(1-(3-(methylamino) piperidin-1-yl)-6-(p-tolyl) pyrrolo[1,2-a]pyrazin-7- yl)benzonitrile hydrochloride::US20240216357, Example 189

SMILES CN[C@@H]1CCCN(C1)c1nccn2c(c(cc12)-c1ccc(cc1)C#N)-c1ccc(C)cc1

InChI Key InChIKey=FPUUYHBJKPSCGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683233   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683233(US20240216357, Example 189 | (R)-4-(1-(3-(methylam...)
Affinity DataIC50: 0.290nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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