BDBM683189 4-(5-(4- aminopiperidin-1- yl)-8-(4-chloro- 3-hydroxyphenyl) imidazolo[1,2-c] pyrimidin-7-yl)-2- fluorobenzonitrile formate::US20240216357, Example 142

SMILES NC1CCN(CC1)c1nc(-c2ccc(C#N)c(F)c2)c(-c2ccc(Cl)c(O)c2)c2nccn12

InChI Key InChIKey=XDRVGFZPUVQWMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683189   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683189(US20240216357, Example 142 | 4-(5-(4- aminopiperid...)
Affinity DataIC50: 0.198nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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