BDBM683138 2-(4-aminopiperidin-1- phenyl)-5- (3-hydroxy-4- (2-hydroxy-2-methyl propoxy)phenyl) nicotinonitrile hydrochloride::US20240216357, Example 86

SMILES CC(C)(O)COc1ccc(cc1O)-c1cnc(N2CCC(N)CC2)c(C#N)c1-c1ccc(C#N)c(F)c1

InChI Key InChIKey=UMLKWNNBFMFPRB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683138   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683138(US20240216357, Example 86 | 2-(4-aminopiperidin-1-...)
Affinity DataIC50: 0.147nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
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