BDBM683123 2-(4-aminopiperidin-1- yl)-4-(4-cyano-3- fluorophenyl)- 5-(5-fluoro-3- methylbenzo[d] isoxazol- 6-yl)nicotinonitrile::US20240216357, Example 71

SMILES Cc1noc2cc(c(F)cc12)-c1cnc(N2CCC(N)CC2)c(C#N)c1-c1ccc(C#N)c(F)c1

InChI Key InChIKey=REWYNMAXKJDRJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683123   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683123(US20240216357, Example 71 | 2-(4-aminopiperidin-1-...)
Affinity DataIC50: 0.300nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
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Date in BDB:
10/11/2024
Entry Details
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TargetCytochrome P450 3A4(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683123(US20240216357, Example 71 | 2-(4-aminopiperidin-1-...)
Affinity DataIC50: 4.30E+3nMAssay Description:Using mixed human liver microsomes as a CYP 450 enzyme source, specific probe substrates of respective CYP isoenzymes (2 substrates for CYP 3A4) are ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent