BDBM683062 Preparation of 4-(5-(3-amino-8-azabicyclo[3.2.1]octane-8-carbonyl)-2-(2-fluoro-4-methylphenyl)thiophen-3-yl)-2-fluorobenzonitrile hydrochloride::US20240216357, Example 6::US20240216357, Example 7

SMILES Cc1ccc(-c2sc(cc2-c2ccc(C#N)c(F)c2)C(=O)N2C3CCC2CC(N)C3)c(F)c1

InChI Key InChIKey=AKGNFHRHHYSFRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 683062   

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683062(US20240216357, Example 6 | Preparation of 4-(5-(3-...)
Affinity DataIC50: 0.300nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Sichuan Huiyu Pharmaceutical Co.

US Patent
LigandPNGBDBM683062(US20240216357, Example 6 | Preparation of 4-(5-(3-...)
Affinity DataIC50: 0.400nMAssay Description:The effects of compounds on LSD1 enzyme activity are detected by an HTRF technology to evaluate their inhibition levels on LSD1 enzyme activity. Firs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2024
Entry Details
Go to US Patent