BDBM683050 1-(4-chloro-2-fluorobenzyl)-6-(imidazo[1,2-b]pyridazin-3-yl)-3-methyl-1H-pyrazolo[4,3-b]pyridine::US20240209001, Example 8a

SMILES Cc1nn(Cc2ccc(Cl)cc2F)c2cc(cnc12)-c1cnc2cccnn12

InChI Key InChIKey=AMNILJSOPRVHOM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 683050   

TargetTyrosine-protein kinase JAK1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM683050(US20240209001, Example 8a | 1-(4-chloro-2-fluorobe...)
Affinity DataIC50: 200nMAssay Description:The objective of this study was to assess the capability of compounds to inhibit all 4 JAK isoforms activity in a cell-free environment. Assay for JA...More data for this Ligand-Target Pair
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Date in BDB:
10/4/2024
Entry Details
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