BDBM682861 7-(isoquinolin-4-yl)-2- (2- (trifluoromethyl)phenyl)- 5,7-diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 22

SMILES FC(F)(F)c1ccccc1C1CC2(C1)NC(=O)N(C2=O)c1cncc2ccccc12

InChI Key InChIKey=IRWXVRNNVAFCHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 682861   

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682861(US20240208970, Compound 22 | 7-(isoquinolin-4-yl)-...)
Affinity DataIC50: 197nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent