BDBM682841 2-(2-chlorophenyl)-7- (phthalazin-1-yl)-5,7- diazaspiro[3.4]octane- 6,8-dione::US20240208970, Compound 49

SMILES Clc1ccccc1C1CC2(C1)NC(=O)N(C2=O)c1cncc2ccccc12

InChI Key InChIKey=XQFMLNUPNCXPRN-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 682841   

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 64nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandPNGBDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed