BDBM68258 Microlactone, 19

SMILES C[C@H](CC=C)OC(=O)c1c(O)cc(O)c(Cl)c1CC(=O)CCCCC=C

InChI Key InChIKey=PPXWDEANQGEGGQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 68258   

TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68258(Microlactone, 19)
Affinity DataIC50: 1.60E+4nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68258(Microlactone, 19)
Affinity DataIC50: 2.70E+4nMAssay Description:A colorimetric assay for the release of inorganic phosphate upon hydrolysis of ATP was used to determine the potency of Hsp 90 inhibitor against enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68258(Microlactone, 19)
Affinity DataIC50: 2.10E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed
TargetATP-dependent molecular chaperone HSP82(Baker's yeast)
University of Nottingham

LigandPNGBDBM68258(Microlactone, 19)
Affinity DataIC50: 2.90E+3nMAssay Description:Binding competition assay with a fluorescent probe.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2011
Entry Details Article
PubMed