BDBM682244 US20240207292, Compound 2054::Val-boroPro

SMILES CC(C)[C@H](N)C(=O)C1CCC[C@H]1B(O)O

InChI Key InChIKey=CXDSYZLZPXATBE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 682244   

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM682244(US20240207292, Compound 2054 | Val-boroPro)
Affinity DataIC50: 5.80nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
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TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM682244(US20240207292, Compound 2054 | Val-boroPro)
Affinity DataIC50: 16nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetPresequence protease, mitochondrial(Human)
Tufts College

US Patent
LigandPNGBDBM682244(US20240207292, Compound 2054 | Val-boroPro)
Affinity DataIC50: 58nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM682244(US20240207292, Compound 2054 | Val-boroPro)
Affinity DataIC50: 1nMAssay Description:Enzymatic activity of DPPIV, DPP8, DPP9, FAP, and PREP was measured at 25° C. on a Molecular Devices M2e multidetection microtiter plate reader, moni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
Go to US Patent