BDBM68220 Type II inhibitor, 15

SMILES CN(C(=O)c1cccc(c1)C(F)(F)F)c1ccc(C)c(c1)N1Cc2cnc(N)nc2N(C)C1=O

InChI Key InChIKey=CMUVKIXSPPYCBV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 68220   

TargetTyrosine-protein kinase ABL1 [1-999,Q252H](Human)
The Scripps Research Institute

LigandPNGBDBM68220(Type II inhibitor, 15)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:An in vitro kinase assay using phosphorylated recombinant human Abl kinase domains to phosphorylate a peptide substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1 [1-999,Q252H](Human)
The Scripps Research Institute

LigandPNGBDBM68220(Type II inhibitor, 15)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:An in vitro kinase assay using dephophorylated conformationally inactive Abl kinase was obtained by treating pure recombinant Abl with Yersinia ester...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2011
Entry Details Article
PubMed