BDBM681803 Step 1; 6-(tert-butyl) 2-methyl 4,7-dihydrothieno[2,3-c]pyridine-2,6(5H)-dicarboxylate (Intermediate 17)::US20240199635, Example C2

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2cc3CCN(Cc3s2)c2cncnc2)cc(c1)C(F)(F)F

InChI Key InChIKey=JOFWACSQYUOVKL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 681803   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM681803(US20240199635, Example C2 | Step 1; 6-(tert-butyl)...)
Affinity DataKi:  2.90E+4nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM681803(US20240199635, Example C2 | Step 1; 6-(tert-butyl)...)
Affinity DataKi:  5.00E+4nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen Europium Kinase Binding assay. The compounds were incubated with 5 n...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent