BDBM681781 US20240199630, Compound 33

SMILES CC1Cc2c(O1)c1nc(C)c(-c3ccnc(Cl)c3)n1nc2NCC1(F)CCNCC1

InChI Key InChIKey=XQGRZBCBXMHIGQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 681781   

TargetSerine/threonine-protein kinase haspin(Human)
CNIO

US Patent
LigandPNGBDBM681781(US20240199630, Compound 33)
Affinity DataIC50: 6.37nMAssay Description:The biochemical assay to measure HASPIN activity relies on the ADP-Glo assay kit (Promega) that determines the amount of ADP as direct product of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase haspin(Human)
CNIO

US Patent
LigandPNGBDBM681781(US20240199630, Compound 33)
Affinity DataIC50: 6.37nMAssay Description:The biochemical assay to measure HASPIN activity relies on the ADP-Glo assay kit (Promega) that determines the amount of ADP as direct product of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent