BDBM681242 N-(4-((R*)-2-(2,6-Difluorophenyl)propyl)-6-(((R)-1-hydroxy-4-methylpentan-2-yl)amino)-1,3,5-triazin-2-yl)methanesulfonamide (Isomer 2)::US20240199558, Example 78

SMILES CC(C)C[C@H](CO)Nc1nc(C[C@@H](C)c2c(F)cccc2F)nc(NS(C)(=O)=O)n1

InChI Key InChIKey=YCCMQKXGRNNWBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 681242   

TargetCX3C chemokine receptor 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM681242(US20240199558, Example 78 | N-(4-((R*)-2-(2,6-Difl...)
Affinity DataIC50: 22nMAssay Description:CHO-hCX3CR1 membranes (5 μg per well) together with different concentrations of antagonistic compound were incubated in 50 mM HEPES (pH 7.4), 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
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