BDBM68089 (2E,6E)-2,6-bis(4-pyridylmethylene)cyclohexanone::(2E,6E)-2,6-bis(pyridin-4-ylmethylene)cyclohexanone::(2E,6E)-2,6-bis(pyridin-4-ylmethylidene)-1-cyclohexanone::(2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan-1-one::MLS000729928::SMR000308205::cid_6018993

SMILES O=C1\C(CCC\C1=C/c1ccncc1)=C\c1ccncc1

InChI Key InChIKey=CYVVJSKZRBZHAV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 68089   

TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM68089((2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan...)
Affinity DataIC50: 2.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay
TargetX-box-binding protein 1(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM68089((2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan...)
Affinity DataIC50: 3.67E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetDNA damage-inducible transcript 3 protein(Mouse)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM68089((2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan...)
Affinity DataIC50: 2.13E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetGlutathione reductase, mitochondrial(Human)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM68089((2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM68089((2E,6E)-2,6-bis(pyridin-4-ylmethylidene)cyclohexan...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed