BDBM680887 US20240199525, Compound BPDA3

SMILES CCCCCCCCCOc1ccc(cc1C(O)=O)-c1cccc(c1)C(O)=O

InChI Key InChIKey=QARIHYFKTQTHPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680887   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
West Virginia University

Curated by ChEMBL
LigandPNGBDBM680887(US20240199525, Compound BPDA3)
Affinity DataIC50: 2.83E+4nMAssay Description:Inhibition of SHP2 (unknown origin) PTPase activity using DiFMUP as substrate incubated for 20 mins by fluorescence plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
West Virginia University

US Patent
LigandPNGBDBM680887(US20240199525, Compound BPDA3)
Affinity DataIC50: 2.83E+4nMAssay Description:First, the GST fusion of the PTP domains of SHP2, SHP1, and PTP1B were produced and purified as reported by us previously.32 The reactions were perfo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2024
Entry Details
Go to US Patent