BDBM680603 7-Fluoro-1-(2-{6-[4-(1H-imidazol-4-yl)-3-methoxy-phenyl]-pyrimidin-4-ylamino}- ethyl)-4-methoxy-1H-indole-2-carbonitrile::US12011444, Example 818

SMILES COc1cc(ccc1-c1c[nH]cn1)-c1cc(NCCn2c(cc3c(OC)ccc(F)c23)C#N)ncn1

InChI Key InChIKey=INVPONZRVHWMJS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680603   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680603(US12011444, Example 818 | 7-Fluoro-1-(2-{6-[4-(1H-...)
Affinity DataIC50: 2nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680603(US12011444, Example 818 | 7-Fluoro-1-(2-{6-[4-(1H-...)
Affinity DataIC50: 1nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent