BDBM680172 US12011444, Example 387::{6-[4-(5-Methylamino-[1,3,4]thiadiazol-2-yl)-phenyl]-pyrimidin-4-yl}-[2-(2-methyl-indol- 1-yl)-ethyl]-amine

SMILES CNc1nnc(s1)-c1ccc(cc1)-c1cc(NCCn2c(C)cc3ccccc23)ncn1

InChI Key InChIKey=YQASIALJGUHYEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680172   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680172(US12011444, Example 387 | {6-[4-(5-Methylamino-[1,...)
Affinity DataIC50: 2nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680172(US12011444, Example 387 | {6-[4-(5-Methylamino-[1,...)
Affinity DataIC50: 556nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent