BDBM680089 US12011444, Example 304::{6-[4-(3-Amino-isoxazol-5-yl)-phenyl]-pyrimidin-4-yl}-[2-(7-fluoro-4-methoxy-2-methyl- indol-1-yl)-ethyl]-amine

SMILES COc1ccc(F)c2n(CCNc3cc(ncn3)-c3ccc(cc3)-c3cc(N)no3)c(C)cc12

InChI Key InChIKey=PFKRLHKDENAIRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 680089   

TargetProstaglandin E2 receptor EP2 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680089(US12011444, Example 304 | {6-[4-(3-Amino-isoxazol-...)
Affinity DataIC50: 2nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent

TargetProstaglandin E2 receptor EP4 subtype(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM680089(US12011444, Example 304 | {6-[4-(3-Amino-isoxazol-...)
Affinity DataIC50: 12nMAssay Description:Stock solutions of test compounds are made at a concentration of 10 mM in DMSO, and serially diluted in DMSO to concentrations required for inhibitio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2024
Entry Details
Go to US Patent